Effect of NIR laser therapy by MLS- MiS source against neuropathic pain in rats: in vivo and ex vivo analysis
Neuropathic pain is the result of damage (due to injury or disease) to the nervous system (including nerves), spinal cord and other central nervous system regions. Neuropathy patients suffer from spontaneous pain, allodynia (pain response to normally innocuous stimuli) and hyperalgesia (aggravated pain evoked by noxious stimuli) that interferes with their quality of life. Several experimental models have been developed to better understand neuropathy. The chronic constriction injury (CCI) model, developed by Bennett and Xie, is a widely used model of mononeuropathy that replicates in rats most of the symptoms occurring in patients.